(Associate) Principal Translational Medicine Scientist
Typical Accountabilities:
Support China-specific activities related to Translational Medicine (TM) clinical studies. Working with the Head of China TM, TM Leads (TMLs) and other functions to deliver clinical testing and translational science activities including: patient selection and translational science test deployment in partner laboratories, monitoring assay data for quality control, prepare study reports for presentation. Accountable for scientific and regulatory aspects of TM activity in third-party multi-disciplinary clinical laboratories and alliance partners for designated clinical projects.
- Assess and execute clinical translational biomarker plan by following established TM strategy, ensure individual clinical studies fits China-specific requirements, including HGR, by supporting TMLs in with respect to clinical testing deployment in China, including: Protocol drafting, recommendations of diagnostic systems, laboratories and/or partners for local testing options.
- Collaborate with and provide scientific expertise to clinical project teams to enable indication selection, early indication of biological activity and patient stratification/selection, especially to address China-specific clinical questions
- Ensure complex clinical assays developed and validated are fit for purpose by working with local vendors and leveraging expertise from global colleagues.
- Contribute to and ensure the quality of Translational Medicine clinical study reports, data reviews and interpretations, presentations, scientific publications and recommendations to development teams and management, including supporting China HGR (Human Genetic Resources) applications for defined TM projects
- Present internal communications on China-specific testing for defined TM projects; liaise with individual TML's with overall responsibility for individual projects to develop communications plan.
Education, Qualifications, Skills and Experience
Essential
- Master’s/MD/PhD degree required, with at least 2 years of relevant experience in the biopharmaceutical industry with understanding of clinical development process and key activities in translational medicine and how they contribute to achieving business objectives.
- Scientific knowledge in Oncology and literature with experience in biomarker related area(s).
- Experience of delivery and interpretation of data for biomarker projects
Skills & Capabilities
- Ability to communicate to stakeholders translational science findings and impact through oral presentations and progress reports
- Ability to identify risks and escalate appropriately
- Good interpersonal skills and ability to act as an ambassador for TM/AZ internally and externally
- Excellent organisational skills, with the proven ability to deliver high quality work under pressure and against tight timelines
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.
